Each year Chicago area children's hospitals conduct
clinical trials and research projects in the hope of uncovering new
treatments and answers for illness, health and developmental issues
Spinal Cord Injury and Quality of Life
This project will examine psychosocial outcomes among
youth with spinal cord injury and their primary caregivers.
Specifically, this study is assessing levels of community
participation, health-related quality of life, anxiety, depression
and coping among children with SCI, as well as anxiety, depression
and coping among their caregivers.
How to participate: Participants should be
between 1 and 18 years old and have been injured for at least one
year. Contact Sara J. Klaas, (773) 385-5448 or email email@example.com.
Natural History of Osteogenesis
Osteogenesis Imperfecta (OI) is a congenital disease that
causes extremely weak bones. This longitudinal study involves
collecting and analyzing information about past medical history,
current medical history and overall health of people who have OI.
Enrollment of children with OI can help reveal treatable problems
early. Enrollment of adults as well as children will help uncover
issues previously not known to be associated with OI and about
long-term effects of treatments.
How to participate: Shriners is one of six U.S.
centers enrolling children and adults into this study. People of
all ages and all types of OI are needed. Study participants are
required to visit Shriners, or another participating center, once a
year for five years. Each person will receive an extensive annual
physical exam, including various diagnostic studies. Contact Angela
Caudill, (773) 622-5400 ext. 5271 or email firstname.lastname@example.org.
Nationwide Children's Study
Dr. Daniel Johnson is part of a nationwide team of
researchers trying to see how the environment affects growing
children. The National Children's Study will take soil, air and
water samples from homes and neighborhoods nationwide. At least
4,000 of those children will come from the Chicagoland area.
Johnson and the other researchers will track these children for 21
How to participate: The study is enrolling women
who are pregnant or plan to become pregnant soon. Call (866)
315-7124 or visit the National Children's Study online at
Sleep Disorders in Children
Dr. Leila Kheirandish-Gozal is investigating how poor
sleep in children can affect the cardiovascular system. Her sleep
research team is looking for evidence that sleep disorders
potentially lead to heart attacks, diabetes and other chronic
conditions later in life. They are also watching the sleep patterns
of healthy weight and overweight children, looking for evidence of
a molecular mechanism triggered by poor sleep that interrupts the
child's metabolism or encourages weight gain.
How to participate: Any family with a child
struggling with poor sleep may contact the Pediatric Sleep Medicine
Clinic, (773) 702-1242.
Dr. Susan Cohn is working on developing just the right
combination of treatments to beat neuroblastoma, the most common
cancer in infants. Her research is building off the groundbreaking
study she led with other Children's Oncology Group physicians last
year, which found that children treated with immunotherapy after a
stem cell transplant had a 20 percent increase in disease-free
How to participate: Clinical trials are ongoing,
testing a number of new medicines in children who have failed
conventional treatment. For any child with newly diagnosed
neuroblastoma, or who has relapsed after treatment, and is
interested in the trials, call (773) 702-6808.
Food Allergy Study
Thirty years ago, food allergy was extremely rare. Today,
4.3 million U.S. children suffer from this potentially
life-threatening condition. Dr. Xiaoban Wang and researchers hope
to find answers to the causes of food allergies, how they can be
predicted and prevented, and treatments.
How to participate: Eligible families in Chicago
and suburbs should have at least one food allergy-affected child
(age birth to 21). Participants will complete a questionnaire about
their child's environmental exposures, diet, lifestyle and specific
allergies. A clinical evaluation will be conducted to measure the
child's height, weight, blood pressure and lung function. A small
blood sample will be taken and allergy skin tests administered.
Each participant will receive a $25 gift card to Target, free
parking and additional gift card(s) to cover travel expenses.
Contact the Children's Memorial Food Allergy Study team, (888)
573-1833 or email email@example.com.
Treatment of intermediate-risk neuroblastoma
with surgery and chemotherapy
The purpose of this study, led by Dr. Richarchito Manera,
is to reduce therapy for people with intermediate-risk
neuroblastoma. Participants will be placed into groups and will be
assigned to receive a minimum of two, four or eight cycles of
chemotherapy, respectively, after first undergoing an operation to
remove as much of the primary tumor and involved lymph nodes as
Each child will receive at least two cycles of
chemotherapy about every 21 days. After the initial two months of
treatment, each child will be further classified for the remainder
of the treatment.
How to participate: Specific criteria available
from the Loyola Clinical Trials Office, (708) 216-2026.
Pediatric Acupuncture and Pain
This pilot study hopes to determine the role of
acupuncture in the management of pain, nausea and vomiting in
pediatric, adolescent and young adult patients. According to
research studies, between 30 to 70 percent of pediatric patients
with chronic illness experience pain.
How to participate: Anyone between age 5 and 20
who is experiencing pain, nausea or vomiting may be eligible.
Participants will receive eight acupuncture treatments, plus a
small cash stipend at the completion of each treatment. Contact
Angela Johnson, (312) 563-2531 or email firstname.lastname@example.org.
Pediatric Perennial Allergic
In this study, Dr. James Moy and researchers will evaluate
the effects of an investigational nasal spray in children with
year-round allergy symptoms (perennial allergic
How to participate: Subjects must be 3 to 8 years
old and have perennial allergic rhinitis but otherwise be in good
health. The study will include 11 visits and will last about one
year. Contact Amy Bulbrooke, (312) 563-2647, or email email@example.com.
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